It's Halloween night, and stoner video clerk Stan Helsing (Steve Howey) along with his insanely sexy ex-girlfriend (Diora Baird), his best buddy (Kenan Thompson) and an "exotic dancer/massage therapist" (Desi Lydic) detour into a town cursed by parodies of 6 of the biggest monsters in movie history: Freddy Krueger, Jason, Pinhead, Leatherface, Chucky and Michael Myers.
But when Stan discovers that he's a direct descendant of the legendary monster hunter Van Helsing, the four have to survive a night with the monsters, homicidal hitchhikers, vampire strippers, killer karaoke, and the temptations of lots of hot chicks.