Born in Greensboro, North Carolina, Ken Jeong earned his undergraduate degree at Duke University, his medical degree at the University of North Carolina and completed his internal medicine residency in New Orleans, all while doing stand-up. In 1995, Jeong won the Big Easy Laff Off and was invited to Los Angeles by judges former NBC President Brandon and Improv founder Budd Friedman. Jeong began performing regularly at the Improv and Laugh Factory, and was seen on a number of television shows, including The Office, Entourage and MADtv.
In 2006, Jeong and fellow comedian Mike O'Connell's spoof rap duo, Million Dollar Strong, posted on YouTube, garnering over one million views.
Judd Apatow's 2007 box office smash Knocked Up marked Jeong's feature film debut, in the role of Dr. Kuni. He followed with his first major role, as villain King Argotron, in 2008's Role Models. That same year, he appeared in Pineapple Express (2008) and Step Brothers (2008).
Jeong played Asian mobster Mr. Chow in the hit motion picture The Hangover (2009) and reprised the role for the sequel, The Hangover Part II (2011). Jeong currently plays the recurring role of angry Spanish teacher Senor Chang on the NBC comedy series Community.
Other movies include The Goods: Live Hard, Sell Hard (2009), Couples Retreat (2009), Transformers: The Dark Side of the Moon (2011) and the comedy The Zookeeper (2011) opposite Kevin James. His voice was heard in Despicable Me (2010), with Steve Carell. More recently, Jeong appeared in Pain & Gain (2013) alongside Ed Harris and Mark Wahlberg and The Hangover Part III (2013).
Ken and his wife, Tran, have twin daughters.