Good Luck (2000)

A football star (D'Onofrio) named Ole descends into self-pity and rage after he is blinded as the freak result of a ferocious tackle. He is subsequently befriended by Lemley (Hines), a wheelchair-bound dreamer hoping to enter a whitewater rafting race on Oregon's Rogue River. As the two make their way down the Northwest coast, they bicker about Ole's problems with getting laid and going to the bathroom among other things.