Janma is the story of a mother fighting for her daughter's life. Reema plays a divorcee mother with her only daughter being struck by leukemia. Reema tries hard to find a matching stem cells and bone marrow for her daughter but is unable to find the same. However, a kind hearted doctor advises that only her blood offspring can have the matching stem cells.
So she seeks the help of a gynecologist who advises her against pregnancy as she is already fifty but the distraught mother even convinces her former husband for artificial insemination and she succeeds to beget a child with matching stem cells to save her daughter's life.