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Although the title would indicate that female college students are the targets, this is an equal-opportunity slasher film, as both sexes are victims of gruesome murders. From her hospital bed, Beth (Angela O'Neill) is the lone survivor of the butchery in a sorority house that was home to her family 13 years earlier.
Her brother has killed the entire family, with Beth the only one who escaped death. The repressed memories, along with her most recent weekend nightmare, are retold through a series of flashbacks and horrible hallucinations.