In 1998, following his very public relationship with model Kate Moss, Johnny Depp met French actress Vanessa Paradis while filming their mystery thriller The Ninth Gate, and the rest is European grunge history. The two would go on to spawn a daughter, Lily-Rose Depp in 1999, and a son Jack, in 2002. They appeared to be one of the most stable couples in Hollywood, or in France, where they mainly resided during their over decade-long marriage. So, of course, no one expected him to leave her for his 25-year-old Rum Diary co-star Amber Heard in 2012. Oh well, we all know how that turned out, anyway.