Cast: Christina Applegate, Michael Clarke Duncan, Neil Patrick Harris, Sean Hayes, James Marsden, Bette Midler, Nick Nolte, Joe Pantoliano, Katt Williams, Chris O'Donnell, Jack McBrayer, Fred Armisen, Paul Rodriguez, Roger Moore
In the eternal battle between cats and dogs, one crazed feline has just taken things a paw too far.
Kitty Galore, a former elite agent for spy organization MEOWS, has gone rogue. In 48 hours, she plans to unleash a diabolical device designed to not only bring her canine enemies to heel but take down her former kitty comrades and make the world her scratching post.
Faced with this immediate and unprecedented threat, cats and dogs will be forced to work together for the first time in history in an unlikely alliance to save themselvesand their beloved humansfrom global cat-astrophe.
It's time for the fur to fly.