Nominees: Anna Kendrick, Kristen Bell, Kristen Wiig, Melissa McCarthy, Rebel Wilson
Who will win: Melissa McCarthy — the Oscar nominee bagged this trophy last year and we're predicting it's hers again this year. With hilarious performances in The Boss, Central Intelligence and Ghostbusters, she's comedy gold.
Who should win: Kristen Wiig - Zoolander 2, Sausage Party, Ghostbusters, Masterminds and an uproarious exchange with Steve Carell on the Golden Globes stage easily make Kristen this year's funniest lady. But we're not so sure everyone sees it our way.